[KO Validated] HP1 gamma/CBX3 Rabbit pAb (APR24739N)
產(chǎn)品名稱: [KO Validated] HP1 gamma/CBX3 Rabbit pAb (APR24739N)
英文名稱: [KO Validated] HP1 gamma/CBX3 Rabbit pAb (APR24739N)
產(chǎn)品編號(hào): APR24739N
產(chǎn)品價(jià)格: null
產(chǎn)品產(chǎn)地: 美國(guó)
品牌商標(biāo): Leading Biology
更新時(shí)間: null
使用范圍: WB (Mus musculus) IHC (Mus musculus)
生物谷
- 聯(lián)系人 : 請(qǐng)聯(lián)系郵箱
- 地址 : 上海市徐匯區(qū)光啟城辦公樓3樓
- 郵編 : 100176
- 所在區(qū)域 : 上海
- 電話 : business@bioon.com 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : business@bioon.com
分子量:Calculated MW: 20kDa Observed MW: 23kDa 細(xì)胞定位:Nucleus 稀釋方法:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200 總結(jié):At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
