HLA-DRB5 MaxPab mouse polyclonal antibody (B01)
產品名稱： HLA-DRB5 MaxPab mouse polyclonal antibody (B01)
英文名稱： HLA-DRB5 MaxPab mouse polyclonal antibody (B01)
產品編號： H00003127-B01
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human HLA-DRB5 protein.
- Immunogen:
- HLA-DRB5 (AAH09234, 1 a.a. ~ 266 a.a) full-length human protein.
- Sequence:
- MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDIYNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLLFLGAGLFIYFKNQKGHSGLHPTGLVS
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of HLA-DRB5 expression in transfected 293T cell line (H00003127-T01) by HLA-DRB5 MaxPab polyclonal antibody.
Lane 1: HLA-DRB5 transfected lysate(29.37 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 3127
- GeneBank Accession#:
- BC009234
- Protein Accession#:
- AAH09234
- Gene Name:
- HLA-DRB5
- Gene Alias:
- -
- Gene Description:
- major histocompatibility complex, class II, DR beta 5
- Omim ID:
- 604776
- Gene Ontology:
- Hyperlink
- Gene Summary:
- HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq
- Other Designations:
- HLA class II histocompatibility antigen, DR-5 beta chain,MHC HLA-DR-beta cell surface glycoprotein,MHC HLA-DR-beta chain,MHC class II HLA beta chain,MHC class II antigen,OTTHUMP00000029035,human leucocyte antigen DRB5,leukocyte antigen class II
- Related Disease
- Abortion, Habitual
- Abruptio Placentae
- Alveolar Bone Loss
- Aortic Aneurysm, Abdominal
- Arthritis, Rheumatoid
- Bronchiolitis
- Celiac Disease
- Chronic Disease
- Dementia
- Diabetes Mellitus
- Diabetes Mellitus, Type 1
- Diabetes, Gestational
- Disease Susceptibility
- Echinococcosis, Hepatic
- Encephalomyelitis, Autoimmune, Experimental
- Genetic Predisposition to Disease
- Gingival Hemorrhage
- Graft vs Host Disease
- Hallucinations