人 腫瘤壞死因子相關凋亡誘導配體 蛋白, Fc 標簽, 活性三聚體
產品名稱： 人 腫瘤壞死因子相關凋亡誘導配體 蛋白, Fc 標簽, 活性三聚體
英文名稱： Human TRAIL Protein, Fc Tag, active trimer
產品編號： TRL-H5263
產品價格： 23100
產品產地： 中國
品牌商標： 北京百普賽斯生物科技股份有限公司
更新時間： 2025-09-19T18:06:11
使用范圍： null
| 規格 | 價格 |
| 1mg |
- 聯系人 : 團子
- 地址 : 北京經濟技術開發區宏達北路8號5號樓4層
- 郵編 : 100176
- 所在區域 : 北京
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TRAIL, also known as TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL, TNLG6A and TNF superfamily member 10. The TRAIL gene as a drug target, induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. TRAIL also binds the receptors DcR1 and DcR2, which do not contain a cytoplasmic domain (DcR1) or contain a truncated death domain (DcR2). DcR1 functions as a TRAIL-neutralizing decoy-receptor. The cytoplasmic domain of DcR2 is functional and activates NFkappaB. In cells expressing DcR2, TRAIL binding therefore activates NFkappaB, leading to transcription of genes known to antagonize the death signaling pathway and/or to promote inflammation.