MRE11A FISH Probe
產品名稱： MRE11A FISH Probe
英文名稱： MRE11A FISH Probe
產品編號： FA0294
產品價格： 0
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Entrez GeneID:
- 4361
- Gene Name:
- MRE11A
- Gene Alias:
- ATLD,HNGS1,MRE11,MRE11B
- Gene Description:
- MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- AT-like disease,DNA recombination and repair protein,double-strand break repair protein MRE11A,endo/exonuclease Mre11,meiotic recombination 11 homolog A
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Ataxia Telangiectasia
- Ataxia telangiectasia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Ductal
- DNA Damage
- Genetic Predisposition to Disease
- Glioma
- Hematologic Diseases
- Hodgkin Disease
- Kidney Failure, Chronic
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Multiple Sclerosis
- Neoplasms, Glandular and Epithelial
- Occupational Diseases
- Ovarian cancer