IgG4抗原

其它名稱：免疫球蛋白IgG4蛋白，IgG4 protein，IgG4蛋白

貨號：G7043

應用：Standard

特異性：Human IgG4

來源：重組蛋白

存貯：-20℃

免疫球蛋白IgG，由B淋巴細胞激活的漿細胞分泌產生。是人血清中最豐富的蛋白質之一。IgG又分為四種亞型（IgG1,IgG2，IgG3，IgG4）,最主要的是IgG1,而IgG4占總IgG的5%左右。

產品說明：

IgG1 immunoglobulin is most prevalent (>50%) and the IgG4 variety constitutes less than 5%. IgG4 has disulfide bonds linking the heavy chains unsteadily, allowing their separation and forming 2 antigen-binding sites, so that the bispecific antibody is asymmetric with an unclear in vivo role. IgG4 interacts with the Fc portion of IgG1–3 and not through the Fab-Fc, as occurs with other immunoglobulins, and has rheumatoid factor activity. Therefore, IgG4 has little or no cross-reactivity between antigens and rarely forms immune complexes having no complement activation capacity

This product is for research use only. It is not intended for diagnostic or therapeutic use.

注意事項：

1.本品為蛋白質制劑，未添加任何防腐劑和保護劑，在2-8℃可短期保存

2.本品作為診斷試劑原輔材料，不得直接用于診斷或治療。