MAP2K4 polyclonal antibody
產品名稱： MAP2K4 polyclonal antibody
英文名稱： MAP2K4 polyclonal antibody
產品編號： PAB5570
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAP2K4.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding S80 of human MAP2K4.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation.
Park HS, Kim MS, Huh SH, Park J, Chung J, Kang SS, Choi EJ.J Biol Chem. 2002 Jan 25;277(4):2573-8. Epub 2001 Nov 13.
- Entrez GeneID:
- 6416
- Gene Name:
- MAP2K4
- Gene Alias:
- JNKK,JNKK1,MAPKK4,MEK4,MKK4,PRKMK4,SEK1,SERK1
- Gene Description:
- mitogen-activated protein kinase kinase 4
- Omim ID:
- 601335
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. [provided by RefSeq
- Other Designations:
- JNK activating kinase 1,JNK-activated kinase 1,MAP kinase kinase 4,MAPK/ERK kinase 4,SAPK/ERK kinase 1,c-Jun N-terminal kinase kinase 1,dual specificity mitogen-activated protein kinase kinase 4