RPTOR polyclonal antibody
產品名稱： RPTOR polyclonal antibody
英文名稱： RPTOR polyclonal antibody
產品編號： PAB13419
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of RPTOR.
- Immunogen:
- A synthetic peptide corresponding to internal region 15 amino acids of human RPTOR.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Specificity:
- Raptor has multiple isoforms that may also be recognized by antibody.
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression.
Fingar DC, Blenis J.Oncogene. 2004 Apr 19;23(18):3151-71.
- 2.
- Integration of growth factor and nutrient signaling: implications for cancer biology.
Shamji AF, Nghiem P, Schreiber SL.Mol Cell. 2003 Aug;12(2):271-80.
- 3.
- Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism.
Hara K, Yonezawa K, Weng QP, Kozlowski MT, Belham C, Avruch J.J Biol Chem. 1998 Jun 5;273(23):14484-94.
- Entrez GeneID:
- 57521
- Protein Accession#:
- Q8N122
- Gene Name:
- RPTOR
- Gene Alias:
- KOG1,Mip1
- Gene Description:
- regulatory associated protein of MTOR, complex 1
- Omim ID:
- 607130
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats,regulatory associated protein of mTOR
- Gene Pathway