Anti-ATF4 Polyclonal Antibody

英文名稱
Anti-ATF4 Polyclonal Antibody
別名
CREB-2;CREB2;TAXREB67;TXREB
應用
WB IHC
稀釋比例
WB 1:500-2000. IHC 1:50-200.
交叉反應
Human Mouse Rat
蛋白分子量
39kDa
Gene ID
468
保存
Store at -20°C. Avoid freeze / thaw cycles.
儲存液
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法
Affinity purification
亞型
IgG
免疫原
Recombinant protein of human ATF4
性狀
液體
Public Immunogen Range
Recombinant protein of human ATF4
Subcellular Locations
Cell membrane Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center
Swiss Prot
P18848
克隆類型
Polyclonal Antibody
背景資料
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.