ACVR1C monoclonal antibody (M01), clone 2E3
產(chǎn)品名稱： ACVR1C monoclonal antibody (M01), clone 2E3
英文名稱： ACVR1C monoclonal antibody (M01), clone 2E3
產(chǎn)品編號： H00130399-M01
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 臺灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺灣臺北市內(nèi)湖區(qū)洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺灣
- 電話 : +886-920**1152 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant ACVR1C.
- Immunogen:
- ACVR1C (AAH22530.1, 23 a.a. ~ 112 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- SPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPM
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Applications
- In situ Proximity Ligation Assay (Cell)
- Proximity Ligation Analysis of protein-protein interactions between INHBB and ACVR1C. HeLa cells were stained with anti-INHBB rabbit purified polyclonal 1:1200 and anti-ACVR1C mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
- Entrez GeneID:
- 130399
- GeneBank Accession#:
- BC022530
- Protein Accession#:
- AAH22530.1
- Gene Name:
- ACVR1C
- Gene Alias:
- ACVRLK7,ALK7
- Gene Description:
- activin A receptor, type IC
- Omim ID:
- 608981
- Gene Ontology:
- Hyperlink
- Gene Summary:
- ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM
- Other Designations:
- activin receptor-like kinase 7
- Interactome
