英文名稱 PICK1?
中文名稱?蛋白激酶Cα相互作用蛋白1重組兔單克隆抗體?
別? ? 名 PICK 1; Pick1; PICK1_HUMAN; PRKCA binding protein; PRKCA-binding protein; Prkcabp; Protein interacting with C kinase 1; Protein interacting with PRKCA; Protein interacting with PRKCA 1; Protein kinase C alpha binding protein; Protein kinase C-alpha-binding protein; Protein that interacts with C kinase 1.? ?
研究領域 腫瘤? 細胞生物? 免疫學? 神經生物學? 信號轉導? 激酶和磷酸酶? ?
抗體來源 Rabbit?
克隆類型 Monoclonal?
克 隆 號 4G1?
交叉反應 (predicted: Human, Mouse, Rat, )?
產品應用 WB=1:500-2000 IP=1:10-50?
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.?
分 子 量 46kDa?
細胞定位 細胞漿 細胞膜??
性? ? 狀 Liquid?
濃? ? 度 1mg/ml?
免 疫 原 KLH conjugated synthetic peptide derived from human PICK1:??
亞? ? 型 IgG?
純化方法 affinity purified by Protein A?
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.?
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.?
PubMed PubMed?
產品介紹 Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ACCN3/ACCN2 channel.
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Function:
Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ACCN3/ACCN2 channel.
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Subunit:
Monomer and homodimer.
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Subcellular Location:
Cytoplasm, perinuclear region. Cell junction, synapse. Note=Also present at excitatory synapses.
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Tis