Amyloid β-Protein (1-40)
產品名稱： Amyloid β-Protein (1-40)
英文名稱： Amyloid β-Protein (1-40)
產品編號： HD130002
產品價格： null
產品產地： 武漢
品牌商標： 昊德
更新時間： null
使用范圍：
- 聯系人 :
- 地址 : 武漢市江夏區譚湖一路光谷8號工坊
- 郵編 :
- 所在區域 : 湖北
- 電話 : 189****5746 點擊查看
- 傳真 : 點擊查看
- 郵箱 : dingjimin001@moonbiochem.com
Amyloid β-Protein (1-40)
CompanySerial Number：HD130002
ProductName：Amyloid β-Protein (1-40)
Synonym：
CASNo.：[131438-79-4] net
Sequence(three-letter)：H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OHTrifluoroacetate salt
Sequence(one-letter)： DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV-OHTrifluoroacetatesalt
ConstitutionalFormula：
MolecularFormula： C194H295N53O58S
MolecularWeight：4330.09
References： B.A.Yankneret al., Science, 250, 279 (1990)
M.A.Kowalska and K.Badellino, Biochem. Biophys. Res. Commun., 205, 1829 (1994)
A.Klegeris et al., Biochem. Biophys. Res. Commun., 199, 984 (1994)
M.Pitschke et al., Nat. Med., 4, 832 (1998)
G.Bitan et al., Proc. Natl. Acad. Sci. USA, 100, 330 (2003)
D.M.Walsh and D.J.Selkoe, J. Neurochem., 101, 1172 (2007)
A.Jan et al., Nat. Protoc., 5, 1186 (2010)
Illustration：Amyloidβ-protein (1-40) showed both neurotrophic and neurotoxic effects in dependenceon the neuronal age and the concentration of the β-protein. Aβ 1-40 has beenused as well as Aβ 1-42 to detect amyloid β-protein multimers in thecerebrospinal fluid of Alzheimer's disease patients. H-2972, the inverted Aβ1-40 sequence, can be used as inactive control in experiments employing H-1194.For detailed descriptions of the preparation of wild-type and mutant Aβ 1-40monomers and protofibrils please see the paper of Jan, Hartley, and Lashuel.
ConditionOf Storage: -20± 5 °C