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Human Growth Factors & Cytokines
Recombinant Human IL-22





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		Synonyms :
IL-TIF



		Description :
IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26.  Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions.  Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas.  IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.  Recombinant human IL-22 is a 33.6 kDa non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains.



		Catalog #:
200-22



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by its ability to activate STAT following receptor ligand interaction.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI 



		PubMed Link :
IL-22


Country of Origin :
USA
















        Size A
2μg
$80?
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        Size B
10μg
$195?
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        Size C
1mg
$5200?
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Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.