TGFBI monoclonal antibody, clone k1H12
產品名稱： TGFBI monoclonal antibody, clone k1H12
英文名稱： TGFBI monoclonal antibody, clone k1H12
產品編號： MAB2058
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant TGFBI.
- Immunogen:
- Recombinant protein corresponding to amino acids 502-636 of human TGFBI.
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG2a, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The transforming growth factor-beta-inducible matrix protein (beta)ig-h3 interacts with fibronectin.
Billings PC, Whitbeck JC, Adams CS, Abrams WR, Cohen AJ, Engelsberg BN, Howard PS, Rosenbloom J.J Biol Chem. 2002 Aug 2;277(31):28003-9. Epub 2002 May 28.
- 2.
- BIGH3 mutation spectrum in corneal dystrophies.
Munier FL, Frueh BE, Othenin-Girard P, Uffer S, Cousin P, Wang MX, Heon E, Black GC, Blasi MA, Balestrazzi E, Lorenz B, Escoto R, Barraquer R, Hoeltzenbein M, Gloor B, Fossarello M, Singh AD, Arsenijevic Y, Zografos L, Schorderet DF.Invest Ophthalmol Vis Sci. 2002 Apr;43(4):949-54.
- 3.
- Identification of motifs for cell adhesion within the repeated domains of transforming growth factor-beta-induced gene, betaig-h3.
Kim JE, Kim SJ, Lee BH, Park RW, Kim KS, Kim IS.J Biol Chem. 2000 Oct 6;275(40):30907-15.
- Applications
- Western Blot
- Cell lysates of HeLa (lane 1), Jurkat (lane 2), 293T (lane 3) and the extracts of mouse liver tissue (lane 4) (20 ug) were resolved by SDS-PAGE and probed with TGFBI monoclonal antibody, clone k1H12 (Cat # MAB2058) (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 7045
- Protein Accession#:
- NP_000349
- Gene Name:
- TGFBI
- Gene Alias:
- BIGH3,CDB1,CDG2,CDGG1,CSD,CSD1,CSD2,CSD3,EBMD,LCD1
- Gene Description:
- transforming growth factor, beta-induced, 68kDa
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq
- Other Designations:
- RGD-containing collagen-associated protein,kerato-epithelin