PeproTech Armenian Hamster抗小鼠CD152 (CTLA-4) APC
產(chǎn)品名稱： PeproTech Armenian Hamster抗小鼠CD152 (CTLA-4) APC
英文名稱： Anti-Mouse CD152 (CTLA-4) APC
產(chǎn)品編號： 14612-80-25
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： USA
品牌商標(biāo)： peperotech(BioGems)
更新時間： null
使用范圍： 流式
美國PeproTech(派普泰克)公司中國代表處
- 聯(lián)系人 :
- 地址 :  江蘇省蘇州市工業(yè)園區(qū)星湖街218號A1北座4樓L03
- 郵編 : 215123
- 所在區(qū)域 : 江蘇
- 電話 : 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : peprotech.infochina@thermofisher.com
The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.