FNTA (C-term) Peptide
產品名稱： FNTA (C-term) Peptide
英文名稱： FNTA (C-term) Peptide
產品編號： P1104
產品價格： 0
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
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- 所在區域 : 臺灣
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of FNTA.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human FNTA.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling.
Wang T, Danielson PD, Li BY, Shah PC, Kim SD, Donahoe PK.Science. 1996 Feb 23;271(5252):1120-2.
- 2.
- cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I.
Zhang FL, Diehl RE, Kohl NE, Gibbs JB, Giros B, Casey PJ, Omer CA.J Biol Chem. 1994 Feb 4;269(5):3175-80.
- 3.
- cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences.
Andres DA, Milatovich A, Ozcelik T, Wenzlau JM, Brown MS, Goldstein JL, Francke U.Genomics. 1993 Oct;18(1):105-12.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of A-375 cell lysate (35 ug/lane) with FNTA polyclonal antibody (Cat # PAB4327).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with FNTA polyclonal antibody (Cat # PAB4327) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . BC = breast carcinoma .
- Entrez GeneID:
- 2339
- Protein Accession#:
- NP_002018;P49354
- Gene Name:
- FNTA
- Gene Alias:
- FPTA,MGC99680,PGGT1A,PTAR2
- Gene Description:
- farnesyltransferase, CAAX box, alpha
- Omim ID:
- 134635
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- FTase-alpha,GGTase-I-alpha,farnesyltransferase alpha-subunit,protein prenyltransferase alpha subunit repeat containing 2,ras proteins prenyltransferase alpha,type I protein geranyl-geranyltransferase alpha subunit