GYPB Rabbit pAb (APR21610N)-抗體-抗體-生物在線
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GYPB Rabbit pAb (APR21610N)

GYPB Rabbit pAb (APR21610N)

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產品名稱: GYPB Rabbit pAb (APR21610N)

英文名稱: GYPB Rabbit pAb (APR21610N)

產品編號: APR21610N

產品價格: null

產品產地: 美國

品牌商標: Leading Biology

更新時間: null

使用范圍:

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分子量:Calculated MW: 6kDa/9kDa

細胞定位:Cell membrane, Single-pass type I membrane protein

稀釋方法:IF 1:50 - 1:200

總結:Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.