Recombinant Human IL-1RAcP (Q9NPH3-2, C-Fc-6His)
產(chǎn)品名稱： Recombinant Human IL-1RAcP (Q9NPH3-2, C-Fc-6His)
英文名稱：
產(chǎn)品編號： CA98
產(chǎn)品價格： 0
產(chǎn)品產(chǎn)地： 中國
品牌商標(biāo)： Novoprotein
更新時間： null
使用范圍： null
Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1α, IL1βand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.