Size??100ul
Cat code??220036
Species Cross-reactivity??H
Key Application??WB
Host??Mouse
Clone Number??2H7-B2-D9
Antibody type??Monoclonal antibody
Purified method??
Isotype??IgG1
Molecular Weight??59kDa
Sensitivity??The antibody detects endogenous level of G6PD protein.
Immunogen??Purified recombinant fragment of human G6PD expressed in E. Coli.
UniProt Number??P11413
GeneBank ID??NM_001042351.1
Subcellular location??
Formulation??Ascitic fluid containing 0.03% sodium azide.
Altername??G6PD; G6PD; G6PD_HUMAN; G6PD1; G6pdx; Glucose 6 phosphate 1 dehydrogenase; Glucose 6 phosphate dehydrogenase; Glucose 6 phosphate dehydrogenase, G6PD; Glucose-6-phosphate 1-dehydrogenase; MET19; POS10; Zwf1p;
Gene_symbol??G6PD1
Summary??This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniPort summary  Function??Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
Application Images :??
Western blot detection of G6PD antibody in MCF7,Jurkat and Hela cell lysates using G6PD antibody (dilution 1:500).Predicted band size:59 KDa.Observed band size:59KDa.