Anti-FADD Monoclonal Antibody
產品名稱: Anti-FADD Monoclonal Antibody
英文名稱: Anti-FADD Monoclonal Antibody
產品編號: K001421M
產品價格: null
產品產地: 北京
品牌商標: solarbio
更新時間: 2026-04-10T09:00:03
使用范圍: WB
北京索萊寶科技有限公司
- 聯系人 : 索萊寶-龔思雨
- 地址 : 北京市北京經濟技術開發區環科中路16號26幢3層301
- 郵編 :
- 所在區域 : 北京
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- 郵箱 : 3193328036@qq.com
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Anti-FADD Monoclonal Antibody
品牌:solarbio | 貨號:K001421M
| 英文名稱 | Anti-FADD Monoclonal Antibody |
|---|---|
| 別名 | FADD |
| 應用 | WB |
| 稀釋比例 | WB 1:500. |
| 交叉反應 | Human |
| 蛋白分子量 | 28kDa |
| Gene ID | 8772 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG2a |
| 免疫原 | Recombinant human FADD protein. |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant human FADD protein. |
| Subcellular Locations | Cytosol Nucleus Plasma Membrane |
| Swiss Prot | Q13158 |
| 克隆號 | 5A3-C7-G9 |
| 克隆類型 | Monoclonal Antibody |
| 背景資料 | The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals.Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor,tumor necrosis factor receptor,TNFRSF25,and TNFSF10/TRAIL-receptor,and thus it participates in the death signaling initiated by these receptors.Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein,which allows it to recruit caspase-8,and thereby activate the cysteine protease cascade.Knockout studies in mice also suggest the importance of this protein in early T cell development.[provided by RefSeq,Jul 2008] |
