Phospho-Src-Y529 Rabbit pAb (AMR00866N)
產品名稱: Phospho-Src-Y529 Rabbit pAb (AMR00866N)
英文名稱: Phospho-Src-Y529 Rabbit pAb (AMR00866N)
產品編號: AMR00866N
產品價格: null
產品產地: 美國
品牌商標: Leading Biology
更新時間: null
使用范圍: WB (Human lung cancer cell, Mus musculus, Homo sapiens, Rattus norvegicus) IHC (Mus musculus) IF (Mus musculus, Rattus n
分子量:Calculated MW: 59kDa/60kDa Observed MW: 60KDa 細胞定位:Cell membrane, Cytoplasm, Mitochondrion inner membrane, Nucleus, cytoskeleton 稀釋方法:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:100 - 1:200 總結:This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
