IRF8 polyclonal antibody
產(chǎn)品名稱: IRF8 polyclonal antibody
英文名稱: IRF8 polyclonal antibody
產(chǎn)品編號(hào): PAB12937
產(chǎn)品價(jià)格: null
產(chǎn)品產(chǎn)地: 臺(tái)灣
品牌商標(biāo): Abnova
更新時(shí)間: null
使用范圍:
亞諾法生技股份有限公司(Abnova)
- 聯(lián)系人 :
- 地址 : 臺(tái)灣臺(tái)北市內(nèi)湖區(qū)洲子街 108 號(hào) 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺(tái)灣
- 電話 : +886-920**1152 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of IRF8.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 16 amino acids of human IRF8.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Induction and regulation of IFNs during viral infections.
Malmgaard L.J Interferon Cytokine Res. 2004 Aug;24(8):439-54.
- 2.
- Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells.
Tsujimura H, Tamura T, Kong HJ, Nishiyama A, Ishii KJ, Klinman DM, Ozato K.J Immunol. 2004 Jun 1;172(11):6820-7.
- 3.
- Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription.
Nelson N, Marks MS, Driggers PH, Ozato K.Mol Cell Biol. 1993 Jan;13(1):588-99.
- Entrez GeneID:
- 3394
- Protein Accession#:
- NP_002154
- Gene Name:
- IRF8
- Gene Alias:
- H-ICSBP,ICSBP,ICSBP1,IRF-8
- Gene Description:
- interferon regulatory factor 8
- Omim ID:
- 601565
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq
- Other Designations:
- interferon consensus sequence binding protein 1

