NFKBIA (phospho S32/S36) monoclonal antibody, clone 39A1413-抗體-抗體-生物在線
亞諾法生技股份有限公司（Abnova)
NFKBIA (phospho S32/S36) monoclonal antibody, clone 39A1413

NFKBIA (phospho S32/S36) monoclonal antibody, clone 39A1413

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產品名稱： NFKBIA (phospho S32/S36) monoclonal antibody, clone 39A1413

英文名稱： NFKBIA (phospho S32/S36) monoclonal antibody, clone 39A1413

產品編號： MAB0056

產品價格： null

產品產地： 臺灣

品牌商標： Abnova

更新時間： null

使用范圍：

亞諾法生技股份有限公司（Abnova)
  • 聯系人 :
  • 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
  • 郵編 : 11493
  • 所在區域 : 臺灣
  • 電話 : +886-920**1152 點擊查看
  • 傳真 : 點擊查看
  • 郵箱 : sales@abnova.com.tw

  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic phosphopeptide of NFKBIA.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding S32/S36 of human NFKBIA.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Jurkat cells were treated for 30 min with 100 ug/mL ALLN (N-Acetyl-Leu-Leu-Norleucinal; a Calpain inhibitor and also proteasome inhibitor that prevents IkBa dephosphorylation) followed by incubation with (lanes 2 & 4) or without 1 nM TNF-a (1 & 3). The membranes were blotted with NFKBIA monoclonal antibody, clone 39A1413 (Cat # MAB0056) (lanes 1 & 2) or NFKBIA monoclonal antibody, clone 6A920 (Cat # MAB0057) (that recognizes both non-phospho and phosphorylated forms of IkBa) and immunoreactivity was detected by ECL. The data shows that Cat # MAB0056 detects specifically the phosphorylated form of NFKBIA.
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4792
  • Gene Name:
  • NFKBIA
  • Gene Alias:
  • IKBA,MAD-3,NFKBI
  • Gene Description:
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • Gene Summary:
  • NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM
  • Other Designations:
  • IkappaBalpha,nuclear factor of kappa light chain gene enhancer in B-cells

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