Activin receptor type-2B (ACVR2B) is a transmembrane receptor protein that belongs to the TGF-beta superfamily and is involved in the signaling pathways that regulate various cellular processes. It functions as a receptor for activin, a protein that plays a role in the regulation of cell growth, differentiation, and apoptosis. ACVR2B is particularly important in the context of skeletal and muscle development, as it is involved in the regulation of bone and muscle growth and repair.In addition to its role in normal physiological processes, ACVR2B has garnered significant interest in the field of regenerative medicine and musclerelated conditions. Research has shown that the manipulation of ACVR2B signaling pathways may have therapeutic potential for conditions such as muscle wasting, muscle degeneration, and muscle injuries. This has led to investigations into the development of potential treatments targeting ACVR2B for musclerelated disorders.Overall, ACVR2B is a protein with diverse roles in cellular signaling, development, and disease, and ongoing research continues to uncover its potential as a therapeutic target for various conditions, including musclerelated disorders and cancer.

高純度、高活性、低內毒素、高批間一致性

SDS-PAGE

Figure 1.On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA

Figure 2.Biotinylated Mouse ACVR2B Protein; His-Avi Tag was immobilized at 5 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-ACVR2B hIgG1 Antibody were added.

-85 ~ -65℃保存，收到貨之日起，6個月有效期。避免反復凍融，建議等分分裝為一次實驗使用量，分裝后，-80℃凍存。