β-actin, Rabbit mAb 兔抗β-actin單克隆抗體
產品名稱： β-actin, Rabbit mAb 兔抗β-actin單克隆抗體
英文名稱： β-actin, Rabbit mAb 兔抗β-actin單克隆抗體
產品編號： 30102ES
產品價格： 詢價
產品產地： 翌圣生物
品牌商標： Yeasen
更新時間： 2025-08-01T09:22:50
使用范圍： null
翌圣生物科技（上海）股份有限公司
- 聯系人 : 李自轉
- 地址 : 上海市浦東新區天雄路166弄一號樓三層南單元
- 郵編 : 200030
- 所在區域 : 上海
- 電話 : 139****5640 點擊查看
- 傳真 : 點擊查看
- 郵箱 : lizizhuan@yeasen.com
- 二維碼 : 點擊查看
產品詳情
產品介紹
β-actin（β-肌動蛋白）是已知的肌動蛋白六種異構體中的一種，是由 375 個氨基酸組成的細胞骨架蛋白，分子量大小為 42 kDa 左右。廣泛分布于細胞漿中，表達量非常豐富。β-actin 作為一種管家基因編碼表達的蛋白（Housekeeping Protein），在不同物種之間高度保守。因此，在大多數組織和細胞中常被用作內參，即內部參照（Intern Control）。普遍應用于 Western Blot 實驗來校正蛋白質定量、上樣過程中存在的誤差，確保實驗的準確性。
產品性質
|
Conjugation
|
Unconjugated
|
|
Clonality
|
Monoclonal Antibody
|
|
SwissProt ID
|
P60709
|
|
基因ID
|
60
|
|
MW(kDa)
|
42 kDa
|
|
Host
|
Rabbit
|
|
同工型
|
IgG
|
|
免疫原
|
A synthesized peptide derived from human beta Actin
|
|
Reactivity
|
Human,Mouse,Rat
|
|
Application
|
WB,IHC-P,ICC/IF
|
|
蛋白定位
|
細胞質，細胞骨架
|
|
研究領域
|
細胞生物學，發育生物學
|
產品特色
稀釋比 WB:1/5000-1/10000; IHC:1/50-1/200; IF:1/100-1/200
應用案例
 |
Western blot analysis of beta Actin in (1)HeLa lysates; (2) Human fetal kidney lysates; (3) NIH/3T3 lysates; (4) PC12 lysates using beta Actin antibody. |
 |
Immunofluorescence analysis of beta Actin in Hela using beta Actin antibody. |
 |
Immunohistochemistry analysis of paraffinembedded (1) Human heart; (2) Mouse testis; (3) Human bladder cancer; (4) Mouse heart using beta Actin antibody. |
存儲條件
-25~-15℃保存。
產品文檔
COA
已發表文獻
[1] Yu F, Lu Y, Zhong Z, et al. Mitf Involved in Innate Immunity by Activating Tyrosinase-Mediated Melanin Synthesis in Pteria penguin. Front Immunol. 2021;12:626493. Published 2021 May 20. doi:10.3389/fimmu.2021.626493(IF:7.561)
[2] Fu J, Liu X, Tan L, et al. Modulation of the mechanosensing of mesenchymal stem cells by laser-induced patterning for the acceleration of tissue reconstruction through the Wnt/β-catenin signaling pathway activation. Acta Biomater. 2020;101:152-167. doi:10.1016/j.actbio.2019.10.041(IF:6.638)
[3] Tang L, Zhang C, Yang Q, et al. Melatonin maintains inner blood-retinal barrier via inhibition of p38/TXNIP/NF-κB pathway in diabetic retinopathy. J Cell Physiol. 2021;236(8):5848-5864. doi:10.1002/jcp.30269(IF:6.384)
[4] Li Y, Zhao X, He B, et al. Autophagy Activation by Hypoxia Regulates Angiogenesis and Apoptosis in Oxidized Low-Density Lipoprotein-Induced Preeclampsia. Front Mol Biosci. 2021;8:709751. Published 2021 Sep 9. doi:10.3389/fmolb.2021.709751(IF:5.246)
[5] Liao Y, Zhang H, He D, et al. Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal. Invest Ophthalmol Vis Sci. 2019;60(8):3034-3045. doi:10.1167/iovs.18-26360(IF:3.812)
[6] Jinyu L, Shuying W, Panchan Z, et al. Bone marrow stromal cell antigen 2(BST2) suppresses the migration and invasion of trophoblasts in preeclampsia by downregulating matrix metallopeptidase 2(MMP2). Bioengineered. 2022;13(5):13174-13187. doi:10.1080/21655979.2022.2074712(IF:3.269)
[7] Huang D, Xiong M, Xu X, et al. Bile acids elevated by high-fat feeding induce endoplasmic reticulum stress in intestinal stem cells and contribute to mucosal barrier damage. Biochem Biophys Res Commun. 2020;529(2):289-295. doi:10.1016/j.bbrc.2020.05.226(IF:2.985)
[8] Shi FJ, Xie H, Zhang CY, et al. Is Iba-1 protein expression a sensitive marker for microglia activation in experimental diabetic retinopathy?. Int J Ophthalmol. 2021;14(2):200-208. Published 2021 Feb 18. doi:10.18240/ijo.2021.02.04(IF:1.779)
[9] Jin Z, Shou HF, Liu JW, et al. Spastin interacts with CRMP5 to promote spindle organization in mouse oocytes by severing microtubules. Zygote. 2022;30(1):80-91. doi:10.1017/S0967199421000344(IF:1.442)
[10]JIAXUN X., SHAOJIE M., JIANXIN W., et al. Versatile ginsenoside Rg3 liposomes inhibit tumor metastasis by capturing circulating tumor cells and destroying metastatic niches. Science Advances(2024). doi.org/10.1126/sciadv.abj1262