Recombinant Human BD-4-常用生化試劑-試劑-生物在線

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北京方程生物科技有限公司
Recombinant Human BD-4

Recombinant Human BD-4

商家詢價

產品名稱: Recombinant Human BD-4

英文名稱: Recombinant Human BD-4

產品編號: 300-65

產品價格: 0

產品產地: Peprotech

品牌商標: Peprotech

更新時間: null

使用范圍: null

北京方程生物科技有限公司
  • 聯(lián)系人 :
  • 地址 : 北京市海淀區(qū)安寧莊西路15號
  • 郵編 : 100080
  • 所在區(qū)域 : 北京
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  • 郵箱 : bio_fc@163.com

?Recombinant Human BD-4

Maspin is a non-inhibitory member of the serpin superfamily, a group of 40-60 kDa serine protease inhibitors. Maspin was discovered in 1994 and has been identified in prostate, thymus, testis, intestine, tongue, and lung. Recently Maspin received a great deal of attention due to its potential apoptotic role in cancers. Maspin expression predicts a better prognosis for several types of carcinomas including breast, prostate, colon, and oral squamus cell carcinoma. The level of Maspin is also inversely correlated to VEGF-A, an angiogenic factor. Researchers found that Maspin may play its apoptotic role as an endogenous inhibitor of histone deacetylase I (HDAC I). Therefore, Maspin is a potential personalized marker of Non-Small Cell Lung Carcinoma (NSCLC).

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Recombinant human Maspin (rhMaspin) produced in E. coli is a single non-glycosylated polypeptide chain containing 375 amino acids. rhMaspin has a molecular mass of 42.1 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.

Recombinant Human BD-4

IL-2是一種淋巴因子,可提高人體對病毒、細菌、真菌、原蟲等感染的免疫應答,使細胞毒性T細胞、 自然殺傷細胞和淋巴因子激活的殺傷細胞(LAK)增殖,并升高其余傷活性,進而清除體內腫瘤細胞和病毒感染細胞等,還可促進干擾素、 腫瘤壞死因子等細胞因子的分泌和抗體產生。它是機體免疫應答的核心物質,是一種免疫增強劑,具有抗病毒、抗腫瘤和增強機體免疫功能等作用。最新研究證實:IL-2與內源性腦啡肽具有共同的抗原決定簇和相似的空間結構部份,故它能競爭結合到 中樞神經(jīng)系統(tǒng)中的阿片受體上,提高病閾,產生中樞及外周神經(jīng)鎮(zhèn)痛作用。它還可以在中樞神經(jīng)系統(tǒng)通過某種由阿片受體介導的通路對 交感神經(jīng)系統(tǒng)的興奮施加抑制性影響。

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1、用于腎細胞癌、黑色素瘤。乳腺癌、膀胱癌 肝癌、直腸癌、淋巴癌、肺癌等惡性腫瘤的治療,用于癌性胸腹水的控制,也可以用于淋巴因子激活的殺傷細胞的培養(yǎng)。?

2、用于手術、放療及化療后的腫瘤患者的治療,可增強機體免疫功能。?

3、用于先天或后于免疫缺陷癥的治療,提高病人細胞免疫功能和抗感染能力。?

4、各種自身免疫病的治療:如類風濕性關節(jié)炎、 系統(tǒng)性紅斑狼瘡、干燥綜合征等?

5、對某些病毒性、桿菌性疾病、胞內寄生菌感染性疾病:如乙型肝炎、麻風病、肺結核、白色念珠菌感染等具有一定的治療作用。

1、本品必須在有經(jīng)驗的??漆t(yī)生指導下慎重使用。?

2、藥瓶有裂縫、破損者不能使用。本品加生理鹽水溶解后為透明液體。如通有渾濁、沉淀等現(xiàn)象不宜使用、藥瓶開啟后應一次使用完。不得多次使用。?

3、使用本品從小劑量開始。逐漸增大劑量。應嚴格掌握安全劑量、使用本品低劑量、長療程可降低毒性。并且可維持抗腫瘤活性。?

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4、藥物過量可引起毛細血管滲漏綜合征。表現(xiàn)為低血壓末梢水腫、暫時性腎功能不全等,應立即停用,對癥處理

Recombinant Human BD-4

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300-10 Recombinant Human Oncostatin M 2ug/10ug/
650-14 Recombinant Human Osteoprotegerin(OPG) 10ug/50ug/
130-03 Recombinant Human OTOR 5ug/20ug/
130-13 Recombinant PEDF 5ug/20ug/
310-02 Recombinant Human Scd40 Ligand 10ug/50ug/
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300-28A Recombinant Human SDF-1 a(CXCL12) 2ug/10ug/
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150-05 Human ICAM-1 10ug/50ug/1mg