Recombinant Human BD-4
產品名稱: Recombinant Human BD-4
英文名稱: Recombinant Human BD-4
產品編號: 300-65
產品價格: 0
產品產地: Peprotech
品牌商標: Peprotech
更新時間: null
使用范圍: null
- 聯(lián)系人 :
- 地址 : 北京市海淀區(qū)安寧莊西路15號
- 郵編 : 100080
- 所在區(qū)域 : 北京
- 電話 : 132****8551;153****6903 點擊查看
- 傳真 : 點擊查看
- 郵箱 : bio_fc@163.com
?Recombinant Human BD-4
Maspin is a non-inhibitory member of the serpin superfamily, a group of 40-60 kDa serine protease inhibitors. Maspin was discovered in 1994 and has been identified in prostate, thymus, testis, intestine, tongue, and lung. Recently Maspin received a great deal of attention due to its potential apoptotic role in cancers. Maspin expression predicts a better prognosis for several types of carcinomas including breast, prostate, colon, and oral squamus cell carcinoma. The level of Maspin is also inversely correlated to VEGF-A, an angiogenic factor. Researchers found that Maspin may play its apoptotic role as an endogenous inhibitor of histone deacetylase I (HDAC I). Therefore, Maspin is a potential personalized marker of Non-Small Cell Lung Carcinoma (NSCLC).
?
Recombinant human Maspin (rhMaspin) produced in E. coli is a single non-glycosylated polypeptide chain containing 375 amino acids. rhMaspin has a molecular mass of 42.1 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Recombinant Human BD-4
IL-2是一種淋巴因子,可提高人體對病毒、細菌、真菌、原蟲等感染的免疫應答,使細胞毒性T細胞、 自然殺傷細胞和淋巴因子激活的殺傷細胞(LAK)增殖,并升高其余傷活性,進而清除體內腫瘤細胞和病毒感染細胞等,還可促進干擾素、 腫瘤壞死因子等細胞因子的分泌和抗體產生。它是機體免疫應答的核心物質,是一種免疫增強劑,具有抗病毒、抗腫瘤和增強機體免疫功能等作用。最新研究證實:IL-2與內源性腦啡肽具有共同的抗原決定簇和相似的空間結構部份,故它能競爭結合到 中樞神經(jīng)系統(tǒng)中的阿片受體上,提高病閾,產生中樞及外周神經(jīng)鎮(zhèn)痛作用。它還可以在中樞神經(jīng)系統(tǒng)通過某種由阿片受體介導的通路對 交感神經(jīng)系統(tǒng)的興奮施加抑制性影響。
?
1、用于腎細胞癌、黑色素瘤。乳腺癌、膀胱癌 肝癌、直腸癌、淋巴癌、肺癌等惡性腫瘤的治療,用于癌性胸腹水的控制,也可以用于淋巴因子激活的殺傷細胞的培養(yǎng)。?
2、用于手術、放療及化療后的腫瘤患者的治療,可增強機體免疫功能。?
3、用于先天或后于免疫缺陷癥的治療,提高病人細胞免疫功能和抗感染能力。?
4、各種自身免疫病的治療:如類風濕性關節(jié)炎、 系統(tǒng)性紅斑狼瘡、干燥綜合征等?
5、對某些病毒性、桿菌性疾病、胞內寄生菌感染性疾病:如乙型肝炎、麻風病、肺結核、白色念珠菌感染等具有一定的治療作用。
1、本品必須在有經(jīng)驗的??漆t(yī)生指導下慎重使用。?
2、藥瓶有裂縫、破損者不能使用。本品加生理鹽水溶解后為透明液體。如通有渾濁、沉淀等現(xiàn)象不宜使用、藥瓶開啟后應一次使用完。不得多次使用。?
3、使用本品從小劑量開始。逐漸增大劑量。應嚴格掌握安全劑量、使用本品低劑量、長療程可降低毒性。并且可維持抗腫瘤活性。?
?
4、藥物過量可引起毛細血管滲漏綜合征。表現(xiàn)為低血壓末梢水腫、暫時性腎功能不全等,應立即停用,對癥處理
Recombinant Human BD-4
?
| 120-10 | Recombinant Human NOGGIN | 5ug/20ug/ |
| 300-10 | Recombinant Human Oncostatin M | 2ug/10ug/ |
| 650-14 | Recombinant Human Osteoprotegerin(OPG) | 10ug/50ug/ |
| 130-03 | Recombinant Human OTOR | 5ug/20ug/ |
| 130-13 | Recombinant PEDF | 5ug/20ug/ |
| 310-02 | Recombinant Human Scd40 Ligand | 10ug/50ug/ |
| 300-07 | Recombinant Human SCF | 2ug/10ug/ |
| 300-28A | Recombinant Human SDF-1 a(CXCL12) | 2ug/10ug/ |
| 300-30 | Recombinant Human TARC(CCL17) | 5ug/20ug/ |
| 300-18 | Recombinant Human Thrombopoietin(TPO) | 2ug/10ug/ |
| 300-60 | Recombinant Human Trefoil Factor1 | 5ug/20ug/ |
| 300-62 | Recombinant Human TSLP | 2ug/10ug/ |
| CYT-205 | Recombinant Human Interferon-Alpha 2b | 20ug/100ug/ |
| CYT-204 | Recombinant Human? Interferon-Alpha 2a | 20ug/100ug/ |
| 120-30 | Human DKK-1 | 2ug/10ug/1mg |
| 150-05 | Human ICAM-1 | 10ug/50ug/1mg |
