HK1 monoclonal antibody, clone 3A10
產品名稱： HK1 monoclonal antibody, clone 3A10
英文名稱： HK1 monoclonal antibody, clone 3A10
產品編號： MAB10683
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant HK1.
- Immunogen:
- Recombinant protein corresponding to human HK1.
- Host:
- Mouse
- Theoretical MW (kDa):
- 120
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis using HK1 monoclonal antibody, clone 3A10 (Cat # MAB10683) against Jurkat (1) , HeLa (2) , HepG2 (3) and NIH/3T3 (4) cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human kidney tissues using HK1 monoclonal antibody, clone 3A10 (Cat # MAB10683) with DAB staining.
- Entrez GeneID:
- 3098
- Gene Name:
- HK1
- Gene Alias:
- HK1-ta,HK1-tb,HK1-tc,HKI,HXK1
- Gene Description:
- hexokinase 1
- Omim ID:
- 142600
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019725,brain form hexokinase,glycolytic enzyme
- Gene Pathway
- Amino sugar and nucleotide sugar metabolism
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Fructose and mannose metabolism
- Galactose metabolism
- Glycolysis / Gluconeogenesis
- Insulin signaling pathway
- Metabolic pathways
- Starch and sucrose metabolism
- Streptomycin biosynthesis
- Type II diabetes mellitus