Anti-14-3-3 delta + zeta (phospho T232)抗體-抗體-抗體-生物在線
深圳市宇德立生物科技有限公司
Anti-14-3-3 delta + zeta (phospho T232)抗體

Anti-14-3-3 delta + zeta (phospho T232)抗體

商家詢價

產品名稱： Anti-14-3-3 delta + zeta (phospho T232)抗體

英文名稱： 14-3-3 protein zeta/delta antibody 1433Z_HUMAN antibody KCIP-1 antibody Protein kinase C inhibitor protein 1 antibody YWHAZ antibody

產品編號： ab195909

產品價格： null

產品產地： 英國

品牌商標： abcam

更新時間： null

使用范圍：

深圳市宇德立生物科技有限公司
  • 聯系人 :
  • 地址 : 深圳市寶安區西鄉寶民二路賢基大廈4E
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  • 所在區域 : 廣東
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  • 郵箱 : 1484332550@qq.com

?

  • 特異性ab195909 detects endogenous levels of 14-3-3 delta + zeta only when phosphorylated at Threonine 232.
  • 經測試應用WBmore details
  • 種屬反應性
    與反應:?Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Human 14-3-3 delta + zeta (phospho T232). (Derived from around the phosphorylation site of Threonine 232).
    Database link:?P63104

  • 陽性對照
    • UV treated Jurkat whole cell lysate.

性能

  • 形式Liquid
  • 存放說明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • 存儲溶液pH: 7.4
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 49% PBS, 0.87% Sodium chloride
  • 濃度100 μg 濃度為 1 mg/ml?
  • 純度Immunogen affinity purified
  • 克隆多克隆
  • 同種型IgG

應用

Our?Abpromise guarantee?covers the use of?ab195909?in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

應用 Abreviews 說明
WB ? 1/500 - 1/2000. Predicted molecular weight: 28 kDa.

靶標

  • 功能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
  • 序列相似性Belongs to the 14-3-3 family.
  • 翻譯后修飾The delta, brain-specific form differs from the zeta form in being phosphorylated (By similarity). Phosphorylation on Ser-184 by MAPK8; promotes dissociation of BAX and translocation of BAX to mitochondria. Phosphorylation on Thr-232; inhibits binding of RAF1. Phosphorylated on Ser-58 by PKA and protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion. Phosphorylation on Ser-58 by PKA; disrupts homodimerization and heterodimerization with YHAE and TP53.
  • 細胞定位Cytoplasm. Melanosome. Located to stage I to stage IV melanosomes.
  • Information by UniProt
  • 數據庫鏈接
  • 別名
    • 14-3-3 protein zeta/delta antibody
    • 1433Z_HUMAN antibody
    • KCIP-1 antibody
    see all

Anti-14-3-3 delta + zeta (phospho T232) antibody 圖像

  • All lanes :?Anti-14-3-3 delta + zeta (phospho T232) antibody (ab195909) at 1/500 dilution

    Lane 1 :?UV treated Jurkat whole cell lysate with antigen specific peptide
    Lane 2 :?UV treated Jurkat whole cell lysate

    Lysates/proteins at 12.5 μg per lane.


    Predicted band size :?28 kDa