• 經測試應用WB,?IHC-P,?ICC/IF,?Flow Cytmore details
• 種屬反應性
  與反應:?Mouse, Rat, Chicken, Cow, Dog, Human, Monkey
• 免疫原

  Recombinant fragment within Mouse GAPDH aa 1-150. The exact sequence is proprietary.
  Database link:?P16858

  Run BLAST with?Run BLAST with?
• 陽性對照
  • WB: HeLa, MDBK, COS-1, MDCK, UMNSAH/DF-1, Jurkat, C6 and NIH/3T3 whole cell lysates; Mouse brain and heart lysates; Rat brain, heart, kidney and spleen lysates; Human fetal brain, heart and kidney lysates. IHC-P: Human transitional cell carcinoma of bladder, Mouse spleen and Rat spleen tissues. ICC/IF: HeLa cells. Flow: Jurkat cells.
• 常規說明

  This product is a recombinant rabbit monoclonal antibody.

  Produced using Abcam’s RabMAb^??technology. RabMAb^??technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

  Alternative versions available:

  Anti-GAPDH antibody (Alexa Fluor^??488)?[EPR16884] (ab204276)

  Anti-GAPDH antibody (Alexa Fluor^??647)?[EPR16884] (ab204480)

性能

• 形式Liquid
• 存放說明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
• 存儲溶液Preservative: 0.01% Sodium azide
  Constituents: 59% PBS, 40% Glycerol, 0.05% BSA
• 濃度100 μl 濃度為 1.485 mg/ml?40 μl 濃度為 1.485 mg/ml?10 μl 濃度為 1.485 mg/ml?
  
• 純度Protein A purified
• 克隆單克隆
• 克隆編號EPR16884
• 同種型IgG
• 研究領域
  • Neuroscience
  ?
  • Neurology process
  ?
  • Neurodegenerative disease
  • Huntington's disease

  • Neuroscience
  ?
  • Neurology process
  ?
  • Neurodegenerative disease
  • Alzheimer's disease
  ?
  • Other

  • Isotype/Loading Controls
  ?
  • Loading Controls
  ?
  • GAPDH

  • Signal Transduction
  ?
  • Metabolism
  ?
  • Energy Metabolism

  • Cancer
  ?
  • Cancer Metabolism
  ?
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Metabolism
  ?
  • Pathways and Processes
  ?
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  ?
  • Pathways and Processes
  ?
  • Metabolic signaling pathways
  • Energy transfer pathways
  ?
  • Energy Metabolism

  • Metabolism
  ?
  • Types of disease
  ?
  • Neurodegenerative disease

應用

靶標

• 功能Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity). Glyceraldehyde-3-phosphate dehydrogenase i