食蟹猴 含 C 型凝集素結(jié)構(gòu)域 7A 蛋白, 組氨酸 標(biāo)簽
產(chǎn)品名稱： 食蟹猴 含 C 型凝集素結(jié)構(gòu)域 7A 蛋白, 組氨酸 標(biāo)簽
英文名稱： Cynomolgus CLEC7A Protein, His Tag
產(chǎn)品編號(hào)： CL7-C5243
產(chǎn)品價(jià)格： 29400
產(chǎn)品產(chǎn)地： 中國(guó)
品牌商標(biāo)： 北京百普賽斯生物科技股份有限公司
更新時(shí)間： 2025-09-19T18:06:11
使用范圍： null
| 規(guī)格 | 價(jià)格 |
| 1mg |
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Lectin that functions as pattern recognizing receptor (PRR) specific for beta-1,3-linked and beta-1,6-linked glucans, which constitute cell wall constituents from pathogenic bacteria and fungi (PubMed:11567029, PubMed:12423684). Necessary for the TLR2-mediated inflammatory response and activation of NF-kappa-B: upon beta-glucan binding, recruits SYK via its ITAM motif and promotes a signaling cascade that activates some CARD domain-BCL10-MALT1 (CBM) signalosomes, leading to the activation of NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines (By similarity). Enhances cytokine production in macrophages and dendritic cells (By similarity). Mediates production of reactive oxygen species in the cell (By similarity). Mediates phagocytosis of C.albicans conidia (PubMed:17230442). Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation. Induces phosphorylation of SCIMP after binding beta-glucans (By similarity).