人激肽釋放酶5蛋白, 無標簽
產品名稱： 人激肽釋放酶5蛋白, 無標簽
英文名稱： Human Kallikrein 5 Protein, Tag Free
產品編號： KA5-H5213
產品價格： 3675
產品產地： 中國
品牌商標： 北京百普賽斯生物科技股份有限公司
更新時間： 2025-09-19T18:06:11
使用范圍： null
| 規格 | 價格 |
| 100ug |
- 聯系人 : 團子
- 地址 : 北京經濟技術開發區宏達北路8號5號樓4層
- 郵編 : 100176
- 所在區域 : 北京
- 電話 : 151****8562 點擊查看
- 傳真 : 點擊查看
- 郵箱 : order.cn@acrobiosystems.com
- 二維碼 : 點擊查看
Kallikrein 5(KLK5), a serine protease encoded by the KLK5 gene, regulates skin desquamation by activating kallikrein proteases (e.g., KLK7) and degrading corneodesmosomes. In cancer, KLK5 exhibits dual roles: while overexpressed in colorectal and pancreatic cancers promotes metastasis via ECM degradation, its elevated expression in breast cancer suppresses tumor growth by inhibiting RhoA and modulating the mevalonate pathway. Dysregulated KLK5 activity drives inflammatory skin disorders through excessive cleavage of cathelicidins. Therapeutic strategies include covalent inhibitors for inflammatory diseases and KLK5-enhancing approaches in breast cancer. Serum KLK5 levels serve as biomarkers for fibrosis and cancer prognosis.