Caspase-5 Inhibitor Screening Kit
產品名稱： Caspase-5 Inhibitor Screening Kit
英文名稱： Caspase-5 Inhibitor Screening Kit
產品編號： KA0750
產品價格： 0
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Caspase-5 Inhibitor Screening Kit is used for screening caspase inhibitors using fluorometric methods.
- Reactivity:
- Mammals
- Storage Instruction:
- Store the kit at -20°C.
- Protocol:
Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Cell
- Detection Method:
- Fluorometric
- Regulation Status:
- For research use only (RUO)
- Application Image
- Functional Study
- Entrez GeneID:
- 838
- Gene Name:
- CASP5
- Gene Alias:
- ICE(rel)III,ICEREL-III,ICH-3,MGC141966
- Gene Description:
- caspase 5, apoptosis-related cysteine peptidase
- Omim ID:
- 602665
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000045729,TY protease,caspase 5,caspase 5, apoptosis-related cysteine protease
- Related Disease
- Adenocarcinoma
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hepatitis C, Chronic
- Hodgkin Disease
- Lung Neoplasms
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Multiple Sclerosis
- Occupational Diseases
- Ovarian cancer
- Ovarian Neoplasms
- Prostatic Neoplasms
- Retinoblastoma
- Tobacco Use Disorder
- Waldenstrom Macroglobulinemia
- Werner syndrome