There are four member of the KChiPs (Kv4 potassium channel interacting protein) family. They are all EF hand containing
proteins required for the raffic of channel forming
Kv4 K+ subunits to the plasma membrane (3).
KChiP1 is expressed predominantly in the brain, with
relative abundance in Purkinje cells of the cerebellum, the
reticular nuclei, the medial habenular nuclei, the
hippocampus and the striatum (4). It is expressed in a
subpopulation of parvalbumin-positve neurons, suggesting its
functional relationship with the GABAergic inhibitory
neurons (4).