p53 單克隆抗體: ATTO 633
產(chǎn)品名稱： p53 單克隆抗體: ATTO 633
英文名稱： p53 Monoclonal Antibody: ATTO 633 [Pab 1801]
產(chǎn)品編號(hào)： SMC-183D-A633
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 加拿大
品牌商標(biāo)： StressMarq
更新時(shí)間： null
使用范圍： ELISA, WB, Flow Cyt., IHC-Fr, IHC-P, IP, RIA
StressMarq
- 聯(lián)系人 :
- 地址 : 加拿大
- 郵編 :
- 所在區(qū)域 : 其他
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- 郵箱 : hedyl@stressmarq.com
The p53 protein (tumor protein 53 or TP53) is a DNA-binding cell cycle-regulating transcription factor that governs cell division and the fine balance between cell death and cell survival (1). P53 plays a critical role in tumor suppression and hence it is often described as "the guardian of the genome", "the guardian angel gene", or the "master watchman." This also refers to its role in conserving stability by preventing genome mutation (2). Defects in p53 are linked to >50% of human cancers, and restoring p53 function to these cancer cells can induce growth arrest and apoptosis (3). When p53 has been damaged, it can also lead to autoimmune disorders (4, 5).