PeproTech重組人FAS Receptor 20ug-細(xì)胞/細(xì)菌培養(yǎng)-試劑-生物在線

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美國PeproTech(派普泰克)公司中國代表處
PeproTech重組人FAS Receptor 20ug

PeproTech重組人FAS Receptor 20ug

商家詢價

產(chǎn)品名稱： PeproTech重組人FAS Receptor 20ug

英文名稱： Recombinant Human FAS Receptor

產(chǎn)品編號： 310-20

產(chǎn)品價格： 0

產(chǎn)品產(chǎn)地： 美國

品牌商標(biāo)： PeproTech

更新時間： null

使用范圍： null

美國PeproTech(派普泰克)公司中國代表處
  • 聯(lián)系人 :
  • 地址 :  江蘇省蘇州市工業(yè)園區(qū)星湖街218號A1北座4樓L03
  • 郵編 : 215123
  • 所在區(qū)域 : 江蘇
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  • 傳真 : 點(diǎn)擊查看
  • 郵箱 : peprotech.infochina@thermofisher.com






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Human Growth Factors & Cytokines


Recombinant Human soluble Fas Receptor







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		Synonyms :


soluble Fas receptor (sFasR), TNFRSF6, CD95, Apo I, Fas Antigen







		Description :


Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively.  Binding of FasL to Fas triggers apoptosis in Fas-bearing cells.  The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms.  These active caspases then cleave various cellular substrates leading to the eventual cell death.  sFasR is capable of inhibiting FasL-induced apoptosis by acting as a decoy receptor that serves as a sink for FasL.  The full length Fas (receptor) is a 319 amino acid type I transmembrane protein, which contains a 157 amino acid extracellular domain, a 17 amino acid transmembrane domain, and 145 amino acid cytoplasmic domain.  Recombinant human soluble Fas (sFas Receptor) is a 157 amino acid polypeptide (17.6 kDa) corresponding to the TNFR homologous cysteine rich extracellular domain Fas.







		Catalog #:


310-20







		Source :


E.coli







		Purity :


Greater than 98% by SDS-PAGE gel and HPLC analyses.







		Endotoxin Level :


Endotoxin level is less than 0.1 ng per μg (1EU/μg).







		Biological Activity :


The ED50 was determined by its ability to inhibit the cytotoxicity of Jurkat cells is between 10-15 μg/ml in the presence of 2ng/ml of hFasL.







                AA Sequence :


MRLSSKSVNA QVTDINSKGL ELRKTVTTVE TQNLEGLHHD GQFCHKPCPP GERKARDCTV NGDEPDCVPC QEGKEYTDKA HFSSKCRRCR LCDEGHGLEV EINCTRTQNT KCRCKPNFFC NSTVCEHCDP CTKCEHGIIK ECTLTSNTKC KEEGSRS 







		PubMed Link :


FAS






Country of Origin :


USA


























        Size A
5μg
$80?
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        Size B
20μg
$195?
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        Size C
1mg
$3900?
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Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.










Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.