重組人成纖維細(xì)胞生長因子1
產(chǎn)品名稱： 重組人成纖維細(xì)胞生長因子1
英文名稱： Recombinant human FGF1 protein
產(chǎn)品編號： rp145907
產(chǎn)品價格： 0
產(chǎn)品產(chǎn)地： 上海
品牌商標(biāo)： 阿拉丁
更新時間： 2023-08-04T14:29:19
使用范圍： null
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基本信息
產(chǎn)品名稱Recombinant human FGF1 protein英文名稱Recombinant human FGF1 protein規(guī)格或純度Animal Free, >95% SDS-PAGE, Active, E.coli, No tag, 16-155 aa生物活性Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line in the presence of heparin. The ED?? for this effect is typically <0.5ng/mL.內(nèi)毒素水平< 0.1 EU/μg種屬Human氨基酸Phe16-Asp155序列FNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAES VGEVYIKSTE TGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVG LKKNGSCKRG PRTHYGQKAILFLPLPVSSD蛋白標(biāo)簽No tag蛋白長度Full length proteinCarrier FreeYesAnimalFreeYesAccession#P05230來源Recombinant預(yù)測分子量15.9 kDaSDS-PAGE13.3 kDa, under reducing conditions; 13.3 kDa, under non-reducing conditions.
相關(guān)屬性
特點與好處·Application:FuncS,SDS-PAGE,WB物理外觀Lyophilized儲存緩沖液Lyophilized from a sterile solution containing 50 mM Tris.Cl, pH7.5, 150mM NaCl.復(fù)溶After receiving lyophilized powder protein, centrifuge first, and then r econstitute at 100μg/mL in sterile PBS.儲存溫度-20°C儲存運(yùn)輸條件超低溫冰袋運(yùn)輸穩(wěn)定性與儲存Stable for 12 months from the date of receipt of the product under proper storage andhandling conditions. Avoid repeated freeze-thaw cycles.
常規(guī)信息
基因名FGF1基因 ID2246細(xì)胞定位Secreted. Cytoplasm. Cytoplasm > cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SY序列相似性Belongs to the heparin-binding growth factors family.通路MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton基因別名AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1英文別名Acidic fibroblast growth factor aFGF Beta; endothelial cell growth factor Beta; endothelial cell growth factor; ECGF; ECGF beta; ECGF-beta; ECGFA; ECGFB; Endothelial Cell Growth Factor alpha; Endothelial Cell Growth Factor beta; FGF 1; FGF alpha; Fgf1; FG別名Acidic fibroblast growth factor aFGF Beta; endothelial cell growth factor Beta; endothelial cell growth factor; ECGF; ECGF beta; ECGF-beta; ECGFA; ECGFB; Endothelial Cell Growth Factor alpha; Endothelial Cell Growth Factor beta; FGF 1; FGF alpha; Fgf1; FG
一般描述
Purity
>95% as determined by SDS-PAGE and Coomassie blue staining
Function
The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.
Sequence similarities
Belongs to the heparin-binding growth factors family.
Cellular localization
Secreted. Cytoplasm. Cytoplasm > cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1.
圖片
Protein Bioactivity: Recombinant Human FGF1 Protein (rp145907)
Recombinant Human FGF1 Protein (rp145907)-Protein Bioactivity
Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line in the presence of heparin. The ED50 for this effect is typically <0.5ng/mL.
SDS-PAGE: Recombinant Human FGF1 Protein (rp145907)
Recombinant Human FGF1 Protein (rp145907)-SDS-PAGE
3μg/lane of Recombinant Human FGF1 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie? Blue staining, showing a single band at 13.3 kDa.