LDN193189 (HCl)
產品名稱： LDN193189 (HCl)
英文名稱： LDN193189 (HCl)
產品編號： SM-0005-0010
產品價格： 0
產品產地： 以色列
品牌商標： Biological industries（BI）
更新時間： null
使用范圍： null
- 聯系人 : 市場部
- 地址 : 上海市奉賢區匯豐西路2082號9幢
- 郵編 : 200120
- 所在區域 : 上海
- 電話 : 189****5545 點擊查看
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- 郵箱 : sales@xpbiomed.com
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Product Description
LDN193189 (HCl) is a highly-potent inhibitor of BMP signaling, specifically blocking ALK1 (IC50?of 0.8 nM), ALK2 (IC50?of 0.8 nM), ALK3 (IC50of 5.3 nM), and ALK6 (IC50?of 16.7 nM), and in turn affecting Smad1/5/8 expression (Galvin-Burgess, et al.). LDN193189 (HCl) has been shown to contribute to the differentiation of pluripotent stem cells (PSCs) into functional pancreatic beta cells when combined with CHIR99021 (Cat. No. SM-0001-0010), SANT-1 (Cat. No. SM-0008-0010), Y27632 (Cat. No. SM-0013-0010), Compound E (Cat. No. SM-0002-0010), RepSox (Cat. No. SM-0006-0010), Triiodothyronine Salt (Cat. No. SM-0011-0500) along with other growth factors (Pagliuca, et al.). LDN193189 has also been utilized in the derivation of neural progenitor cells (Edri, et al.), and cortical neurons (Qi, et al.) from PSCs.?
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Product Synonyms:
LDN193189 tetrahydrochloride, LDN-193189, 1062368-62-0?
Constructed from renowned protocols, Biological Industries selection of small molecules will streamline workflows for research in diabetes, neural disorders, and cardiovascular disease.
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?產品官網鏈接：
https://www.bioind.com/worldwide/ldn-193189/
想了解更多種類的小分子，請點擊官網：https://www.bioind.com/worldwide/products/stem-cell-research/small-molecules/?