Anti-EML4-ALK Mouse Monoclonal Antibody-抗體-抗體-生物在線
武漢紐斯特生物技術有限公司
Anti-EML4-ALK Mouse Monoclonal Antibody

Anti-EML4-ALK Mouse Monoclonal Antibody

商家詢價

產品名稱： Anti-EML4-ALK Mouse Monoclonal Antibody

英文名稱： Anti-EML4-ALK Mouse Monoclonal Antibody

產品編號： 26242

產品價格： null

產品產地： 美國

品牌商標： NewEastBio

更新時間： null

使用范圍： ELISA、WB、 IHC

武漢紐斯特生物技術有限公司
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  • 地址 : 武漢市東湖新技術開發區光谷生物城B3-3棟2-3樓
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  • 所在區域 : 湖北
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  • 郵箱 : neweast3@126.com

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EML4-ALK [26242]
[100ul]		 ?

Catalog Number:??26242
Gene Symbol:??EML4-ALK
Description: ??Anti-EML4-ALK Mouse Monoclonal Antibody
Background: ??EML4-ALK is a fusion-type protein kinase that can be found in many tumors, such as anaplastic large cell lymphoma, inflammatory myofibroblastic tumor, neuroblastoma and NSCLC, and so on. It is generated as a result of a small inversion within the short arm of human chromosome 2. EML4-ALK protein often promotes and maintains the malignant behavior of the cancer cells by activating the MAPK, PI3K/AKT and JAK/STAT3 pathways.
Immunogen: ??A synthetic peptide from the internal region of EML4-ALK of human origin.
Applications: ??ELISA, WB, IHC
Recommended Dilutions: ??
ELISA: 1:1000-1:2000?
WB: 1:500-1:1000?
IHC: 1:50-1:100
Concentration: ??1 mg/ml
Host: ??Mouse
Format: ??Liquid
Clonality: ??Monoclonal
Isotype: ??
Purity: ??Purified from ascites
Storage buffer:
Preservative:??no
Constituents:??PBS (without Mg2+?and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:??Recognizes T41A mutant, but not wild-type EML4-ALK of vertebrates.
Storage Conditions:???Store at -20°C. Avoid freeze / thaw cycles
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Western blot:??
Western blot analysis of recombinant EML4-ALK and wildtype proteins. Purified His-tagged EML4-ALK protein (lane 3), corresponding wild-type EML4 protein (lane1) and wild-type ALK protein (lane2) were blotted with anti-EML4-ALK monoclonal antibody (Cat. #26242).
Immunofluorescence:??
Immunofluorescence of cells expressing EML4-ALK proteins with anti-EML4-ALK antibody. HEK293T cells were transfected with pCDNA3-GFP-EML4 (WT) plasmid (left column) or pCDNA3-GFP-ALK (WT) plasmid (middle column) or pCDNA3-GFP-EML4-ALK plasmid (right column), then fixed and stained with anti-EML4-ALK monoclonal antibody (Cat. #26242).