Beta-Amyloid [1-28] Antibody
產品名稱: Beta-Amyloid [1-28] Antibody
英文名稱: Beta-Amyloid [1-28] Antibody
產品編號: 250922
產品價格: null
產品產地: 美國
品牌商標: Abbiotec
更新時間: null
使用范圍: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500
深圳市豪地華拓生物科技有限公司
- 聯系人 :
- 地址 : 深圳市南山創業路中興城5棟518
- 郵編 : 518054
- 所在區域 : 廣東
- 電話 : 132****4656 點擊查看
- 傳真 : 點擊查看
- 郵箱 : order@otwobiotech.com
Beta-amyloid production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. This fragment is the amino terminus (1-28) of beta amyloid.
