AKAP10 polyclonal antibody
產品名稱: AKAP10 polyclonal antibody
英文名稱: AKAP10 polyclonal antibody
產品編號: PAB7481
產品價格: null
產品產地: 臺灣
品牌商標: Abnova
更新時間: null
使用范圍:
亞諾法生技股份有限公司(Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of AKAP10.
- Immunogen:
- A synthetic peptide corresponding to human AKAP10.
- Sequence:
- C-RKVKGKEQEKTSD
- Host:
- Goat
- Theoretical MW (kDa):
- 73.8
- Reactivity:
- Rat
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:64000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Identification and functional analysis of dual-specific A kinase-anchoring protein-2.
Burns-Hamuro LL, Barraclough DM, Taylor SS.Methods Enzymol. 2004;390:354-74.
- Entrez GeneID:
- 11216
- Protein Accession#:
- NP_009133.2
- Gene Name:
- AKAP10
- Gene Alias:
- D-AKAP2,MGC9414,PRKA10
- Gene Description:
- A kinase (PRKA) anchor protein 10
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction. [provided by RefSeq
- Other Designations:
- A-kinase anchor protein 10,dual-specificity A-kinase anchoring protein 2,mitochondrial A kinase PPKA anchor protein 10,protein kinase A anchoring protein 10
- Related Disease
- Adenocarcinoma
- Arrhythmias, Cardiac
- Breast cancer
- Breast Neoplasms
- Colorectal Neoplasms
- Diabetes Mellitus, Type 2
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Hypercholesterolemia
- Hypertension
- Kidney Failure, Chronic
- Long QT Syndrome
- Metabolic Syndrome X
- Myocardial Infarction
- Renal Insufficiency, Chronic
- Werner syndrome

