Size??100ug
Cat code??200654
Species Cross-reactivity??H,M
Key Application??WB
Host??Mouse
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG1
Molecular Weight??160kDa
Sensitivity??This antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins.
Immunogen??Purified recombinant human LRRFIP1 protein fragments expressed in E.coli.
UniProt Number??Q32MZ4
GeneBank ID??NM_004735.3
Subcellular location??Nucleus. Cytoplasm
Formulation??Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername??GC-binding factor 2
TAR RNA-interacting protein
Gene_symbol??GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1 
Summary??null
UniPort summary  Function??Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5′-AGCCCCCGGCG-3′) and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Application Images :??
Western blot detection of LRRFIP1 in Raji,C2C12,MCF7&Jurkat cell lysates using LRRFIP1 antibody (1:1000 diluted).
Predicted band size:89KDa.
Observed band size:160KDa