SH2B3 polyclonal antibody
產品名稱： SH2B3 polyclonal antibody
英文名稱： SH2B3 polyclonal antibody
產品編號： PAB6669
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of SH2B3.
- Immunogen:
- A synthetic peptide corresponding to human SH2B3.
- Sequence:
- NGPALQPSSPC
- Host:
- Goat
- Theoretical MW (kDa):
- 63.2
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:64000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation.
Li Y, He X, Schembri-King J, Jakes S, Hayashi J.J Immunol. 2000 May 15;164(10):5199-206.
- Applications
- Western Blot (Cell lysate)
- SH2B3 polyclonal antibody (Cat # PAB6669) (0.3 ug/mL) staining of MOLT 4 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 10019
- Protein Accession#:
- NP_005466.1
- Gene Name:
- SH2B3
- Gene Alias:
- CELIAC13,LNK
- Gene Description:
- SH2B adaptor protein 3
- Omim ID:
- 605093
- Gene Ontology:
- Hyperlink
- Gene Summary:
- T-cell activation requires stimulation of the T-cell receptor (TCR; see MIM 186880)-CD3 (see CD3Z; MIM 186780) complex, followed by recruitment of an array of intracellular signaling proteins (e.g., GRB2 (MIM 108355) and PLCG1 (MIM 172420)). Mediating the interaction between the extracellular receptors and intracellular signaling pathways are adaptor proteins such as LAT (MIM 602354), TRIM (MIM 604962), and LNK.[supplied by OMIM
- Other Designations:
- lymphocyte adaptor protein
- Gene Pathway