Product:? Anti-LXR, polyclonal
?
?
Cat. No.: PC-402 (100 μg)
Background:
Liver X receptors (LXRs) are oxysterol activated
nuclear? receptors? which? are? involved? in? the
regulation? of? genesis? and? metabolism? of
cholesterols? and? bile? acids.? LXRs? form
heterodimeric? complexes? with? the? retinoic? acid
receptors? (RARs)? once? activated? by? their
respective? oxysterol? ligands.? Two? known
isoforms,? alpha? and? beta,? are? differentially
expressed;? the? alpha? isoform? is? predominantly
expressed in liver, whereas the beta isoform has
been shown to be expressed ubiquitously.
?
Specificity:
The? antibody? detects? 64? kDa? and? 80? kDa
proteins? representing? the? alpha? and? beta
subunits of human LXR.?
?
Species Reactivity:
Human. Other species not tested.?
Immunogen:
Synthetic peptide surrounding amino acid 435 of
human LXR.??
Host:
Rabbit
Format:
100? μg? (0.5 mg/mL? solution)? of? antigen? affinity
purified? rabbit? antibody? in? PBS,? pH? 7.2,
containing? 50? glycerol,? 0.02? sodium? azide
with protein stabilizer.
?
Storage:
Store? at? -20°C.? For? best? results,? aliquot? and
store at -70°C to avoid repeat freeze/thaw cycles.
?
Applications and Suggested Dilutions:.

? Western blots: Use at 2-6 μg/mL.?
The? optimal? dilution? for? a? specific? application
should be determined by the researcher.
Limitations:
For? in vitro? research? use? only.? Not? for? use? in
diagnostics or in humans.
?
Warranty:
No warranties,? expressed? or? implied,? are made
regarding? the? use? of? this? product.? KAMIYA
BIOMEDICAL COMPANY? is? not? liable? for? any
damage,? personal? injury,? or? economic? loss
caused by this product.