ALPL monoclonal antibody (M02), clone 3A7
產品名稱： ALPL monoclonal antibody (M02), clone 3A7
英文名稱： ALPL monoclonal antibody (M02), clone 3A7
產品編號： H00000249-M02
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant ALPL.
- Immunogen:
- ALPL (AAH21289, 91 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- WRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSR
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
- MSDS:
Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 249
- GeneBank Accession#:
- BC021289
- Protein Accession#:
- AAH21289
- Gene Name:
- ALPL
- Gene Alias:
- AP-TNAP,FLJ40094,FLJ93059,HOPS,MGC161443,MGC167935,TNAP,TNSALP
- Gene Description:
- alkaline phosphatase, liver/bone/kidney
- Gene Ontology:
- Hyperlink
- Gene Summary:
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000002971,OTTHUMP00000002972,alkaline phosphatase, tissue-nonspecific isozyme,alkaline phosphomonoesterase,glycerophosphatase,liver/bone/kidney-type alkaline phosphatase,tissue non-specific alkaline phosphatase,tissue-nonspecific ALP
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Cardiovascular Diseases
- Chondrocalcinosis
- Diabetes Complications
- Fractures, Bone
- Genetic Predisposition to Disease
- Hypertension
- Hypophosphatasia
- Kidney Failure, Chronic
- Metabolic Syndrome X
- Neoplasms
- Osteoporosis
- Osteoporosis, Postmenopausal
- Spondylitis, Ankylosing
- Tobacco Use Disorder