Size??100ug
Cat code??200778
Species Cross-reactivity??H,Mk
Key Application??WB,ICC
Host??Mouse
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG1
Molecular Weight??27kDa
Sensitivity??This antibody detects endogenous levels of HSPB1 and does not cross-react with related proteins.
Immunogen??Purified recombinant human HSPB1 protein fragments expressed in E.coli.
UniProt Number??P04792
GeneBank ID??NM_001540
Subcellular location??Cytoplasm. Nucleus. Cytoplasm ? cytoskeleton ? spindle.
Formulation??Purified mouse monoclonal in PBS(pH 7.4) containing  with 0.2% sodium azide, 50% glycerol, 0.1%BSA
Altername??28 kDa heat shock protein;Estrogen-regulated 24 kDa protein;Heat shock 27 kDa protein;Stress-responsive protein 27
Gene_symbol??CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067
Summary??The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).
UniPort summary  Function??Involved in stress resistance and actin organization.
Application Images :??
Western blot detection of HSPB1 in Hela,HsHela,A431，COS7，LNCAP&MCF7 cell lysates and  using HSPB1 antibody (1:1000 diluted). Predicted band size: 23KDa Observed band size:27KDa
Immunocytochemistry stain of Hela using HSPB1 antibody (1:300).