PTK2B (Human) Recombinant Protein
產(chǎn)品名稱： PTK2B (Human) Recombinant Protein
英文名稱： PTK2B (Human) Recombinant Protein
產(chǎn)品編號(hào)： P4767
產(chǎn)品價(jià)格： 0
產(chǎn)品產(chǎn)地： 臺(tái)灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺(tái)灣臺(tái)北市內(nèi)湖區(qū)洲子街 108 號(hào) 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺(tái)灣
- 電話 : +886-920**1152 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PTK2B (NM_004103.3, 1 a.a. - 1009 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.
- Theoretical MW (kDa):
- 145.724
- Form:
- Liquid
- Preparation Method:
- Insect cell (Sf9) expression system
- Purification:
- One-step affinity purification using GSH agarose
- Concentration:
- 0.076 ug/uL
- Activity:
- 6 pmol/ug x min
- Storage Buffer:
- In 50 mM Hepes-NaOH, 100 mM NaCl, pH 7.5. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing
- Quality Control Testing:
- 2 ug/lane SDS-PAGE Stained with Coomassie Blue
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 2185
- Protein Accession#:
- NM_004103.3
- Gene Name:
- PTK2B
- Gene Alias:
- CADTK,CAKB,FADK2,FAK2,FRNK,PKB,PTK,PYK2,RAFTK
- Gene Description:
- PTK2B protein tyrosine kinase 2 beta
- Omim ID:
- 601212
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CAK beta,OTTHUMP00000128275,OTTHUMP00000162913,calcium-dependent tyrosine kinase,cell adhesion kinase beta,focal adhesion kinase 2,proline-rich tyrosine kinase 2,protein kinase B,protein tyrosine kinase 2 beta,related adhesion focal tyrosine kinase
- Interactome
