Caspase-3 Antibody
產(chǎn)品名稱: Caspase-3 Antibody
英文名稱: Caspase-3 Antibody
產(chǎn)品編號(hào): 250573
產(chǎn)品價(jià)格: null
產(chǎn)品產(chǎn)地: 美國(guó)
品牌商標(biāo): Abbiotec
更新時(shí)間: null
使用范圍: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500
深圳市豪地華拓生物科技有限公司
- 聯(lián)系人 :
- 地址 : 深圳市南山創(chuàng)業(yè)路中興城5棟518
- 郵編 : 518054
- 所在區(qū)域 : 廣東
- 電話 : 132****4656 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : order@otwobiotech.com
Caspase-3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis, Caspase-3 proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-|-Gly-217 bond as well as cleaving and activating the sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. In addition Caspase-3 cleaves and activates caspase-6, -7, -9.
