IKBKB monoclonal antibody, clone 10A2-抗體-抗體-生物在線

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亞諾法生技股份有限公司(Abnova)
IKBKB monoclonal antibody, clone 10A2

IKBKB monoclonal antibody, clone 10A2

商家詢價

產(chǎn)品名稱: IKBKB monoclonal antibody, clone 10A2

英文名稱: IKBKB monoclonal antibody, clone 10A2

產(chǎn)品編號: MAB10695

產(chǎn)品價格: null

產(chǎn)品產(chǎn)地: 臺灣

品牌商標: Abnova

更新時間: null

使用范圍:

亞諾法生技股份有限公司(Abnova)
  • 聯(lián)系人 :
  • 地址 : 臺灣臺北市內(nèi)湖區(qū)洲子街 108 號 9 樓
  • 郵編 : 11493
  • 所在區(qū)域 : 臺灣
  • 電話 : +886-920**1152 點擊查看
  • 傳真 : 點擊查看
  • 郵箱 : sales@abnova.com.tw

  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant IKBKB.
  • Immunogen:
  • Recombinant protein corresponding to human IKBKB.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis using IKBKB monoclonal antibody, clone 10A2 (Cat # MAB10695) against truncated IKBKB recombinant protein (1) and K-562 cell lysate (2) .
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3551
  • Gene Name:
  • IKBKB
  • Gene Alias:
  • FLJ40509,IKK-beta,IKK2,IKKB,MGC131801,NFKBIKB
  • Gene Description:
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • Gene Summary:
  • NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM
  • Other Designations:
  • inhibitor of nuclear factor kappa B kinase beta subunit,nuclear factor NF-kappa-B inhibitor kinase beta
  • Interactome

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