ITGA2B monoclonal antibody, clone MEM-06 (PerCP)
產(chǎn)品名稱： ITGA2B monoclonal antibody, clone MEM-06 (PerCP)
英文名稱： ITGA2B monoclonal antibody, clone MEM-06 (PerCP)
產(chǎn)品編號： MAB10235
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺灣臺北市內(nèi)湖區(qū)洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against of ITGA2B.
- Immunogen:
- Leukocytes of patient suffering from LGL-type leukaemia.
- Host:
- Mouse
- Theoretical MW (kDa):
- 23, 120
- Reactivity:
- Human
- Specificity:
- ITGA2B (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). ITGA2B is mainly expressed on platelets and megakaryocytes.
- Form:
- Liquid
- Conjugation:
- PerCP
- Purification:
- Size-exclusion chromatography purification
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Recommend Usage:
- Flow Cytometry (10 uL reagent/100 uL of whole blood or 106 cells)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 3674
- Gene Name:
- ITGA2B
- Gene Alias:
- CD41,CD41B,GP2B,GPIIb,GTA,HPA3
- Gene Description:
- integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq
- Other Designations:
- integrin alpha 2b,platelet fibrinogen receptor, alpha subunit,platelet-specific antigen BAK
- Related Disease
- Abortion, Spontaneous
- Acute Chest Syndrome
- Acute Disease
- Alzheimer Disease
- Alzheimer disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Angina, Unstable
- Antiphospholipid Syndrome
- Arterial Occlusive Diseases
- Arteriosclerosis
- Atherosclerosis
- Brain Ischemia
- Cardiovascular Diseases
- Carotid Stenosis
- Cerebrovascular Accident
- Cerebrovascular Disorders
- Coronary Artery Disease
- Coronary Disease