Size??100ug
Cat code??200670
Species Cross-reactivity??H,M
Key Application??WB
Host??Mouse
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG1
Molecular Weight??37kDa
Sensitivity??This antibody detects endogenous levels CALU(C-terminus) and does not cross-react with related proteins.
Immunogen??Purified recombinant human CALU(C-terminus) protein fragments expressed in E.coli.
UniProt Number??O43852
GeneBank ID??NM_001219
Subcellular location??Endoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen
Formulation??Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
Altername??Crocalbin,IEF SSP 9302
Gene_symbol??null
Summary??The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.
UniPort summary  Function??Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity
Application Images :??
Western blot detection of CALU in SW480，mouse intestine &A431 cell lysates and  using CALU  antibody (1:1000 diluted). Predicted band size: 37KDa Observed band size:45KDa