Recombinant Murine IL-1β 211-11B Peprotech細胞因子
產品名稱: Recombinant Murine IL-1β 211-11B Peprotech細胞因子
英文名稱: Recombinant Human IL-11
產品編號: 211-11B
產品價格: 0
產品產地: 美國
品牌商標: Peprotech
更新時間: null
使用范圍: null
北京雅安達生物技術有限公司
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Recombinant Murine IL-1β
Catalog Number:
211-11B
Synonyms:
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Description:
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant murine IL-1β is a 17.5 kDa protein containing 153 amino acid residues.
AA Sequence:
MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.002 ng/ml, corresponding to a specific activity of ≥ 5 x 108 units/mg.
Cross Reactivity:
Human, Monkey, Pig, Rat, Mouse + Chicken, Mouse, N/A, Mouse + Bacteria
Research Interests:
| Angiogenesis/ Cardiovascular | Cancer | ||
| Diabetes / Weight Regulation | Immune System | ||
| Inflammation | Neurobiology | ||
| Proliferation | Stem Cells & Differentiation | ||
| Wound Healing | Allergy | ||
| Transplantation | |||
Country of Origin:
USA
